Cancer neuropathic pain: overview of current status and future objectives.
نویسندگان
چکیده
Disclosures: Frederick H. Hausheer: Employment/leadership position: BioNumerik Pharmaceuticals, Inc., KI Pharmaceuticals, Inc.; Intellectual property rights/inventor/patent holder: BioNumerik Pharmaceuticals, Inc.; Ownership interest: BioNumerik Pharmaceuticals, Inc.; Kathleen M. Foley: Consultant/advisory role: NCCN, NCIBCA. The content of this article has been reviewed by independent peer reviewers to ensure that it is balanced, objective, and free from commercial bias. No financial relationships relevant to the content of this article have been disclosed by the independent peer reviewers.
منابع مشابه
Analgesic Effect of a Single Dose of Adenosine for Neuropathic Pain Reduction in a Patient with Primitive Neuroechtodermal Tumor
Background: We report the analgesic efficacy of lumbar epidural adenosine injection in reducing the chronic neuropathic pain in a patient with primitive neuroectodermal tumor. Report of the Case: In this case report a 13-year-old male with primary neuroectodermal tumor (PNET) was administered in epidural space with adenosine to reduce his pain. The patient received 10ml of 0.25% ropivacaine ...
متن کاملRecent advances in understanding pain mechanisms provide future directions for pain management.
PURPOSE/OBJECTIVES To review current knowledge of neurobiologic mechanisms that generate and maintain chronic pain and to explain how they might be applied in targeting treatment of chronic, inflammatory, and neuropathic pain syndromes. DATA SOURCES Published research, literature review articles, and abstracts as well as national statistics. DATA SYNTHESIS Treatment for chronic pain associa...
متن کاملAnalgesic Effect of Bumetanide on Neuropathic Pain in Patients With Spinal Cord Injury
Objectives: The current study evaluated the analgesic effects of bumetanide as an adjunctive in the management of neuropathic pain following spinal cord injury (SCI). The peripheral expression of Na-K-Cl cotransporter-1 (NKCC1) and K-Cl cotransporter-2 (KCC2) genes in polymorphonuclear lymphocytes (PMLs) was assessed as a possible biomarker indicating central mechanisms underlying the observed ...
متن کاملRecommendations for the pharmacological management of neuropathic pain: an overview and literature update.
The Neuropathic Pain Special Interest Group of the International Association for the Study of Pain recently sponsored the development of evidence-based guidelines for the pharmacological treatment of neuropathic pain. Tricyclic antidepressants, dual reuptake inhibitors of serotonin and norepinephrine, calcium channel alpha(2)-delta ligands (ie, gabapentin and pregabalin), and topical lidocaine ...
متن کاملEffect of Paroxetine on the Neuropathic Pain: A Molecular Study
Background: Neuropathic pain due to damage to the peripheral nerve has influenced millions of people living all over the world. It has been shown that paroxetine can relieve neuropathic pain. Recently, the role of some proteins like BDNF, GABAA receptor, and KCC2 transporter in the occurrence of neuropathic pain has been documented. In the current study, the expression of these proteins affecte...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The oncologist
دوره 15 Suppl 2 شماره
صفحات -
تاریخ انتشار 2010